Plasma neutrophil gelatinase-associated lipocalin as a single test rule out biomarker for acute kidney injury: A cross-sectional study in patients admitted to the emergency department

The study illustrates that the value of a single measurement of pNGAL is primarily in excluding AKI whereas it`s poorer in predicting the presence of AKI. When diagnosing AKI with pCr the optimal baseline pCr level is the mean of available pCr (mb-pCr) measurements from up to a year prior to the current event.

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Publication Details

Journal
PLoS ONE
Published
2025-01-10
DOI
https://doi.org/10.1371/journal.pone.0316897
Citations
2
Primary Topic
Acute Kidney Injury Research
Type
article
Field-Weighted Citation Impact
2.86

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article

Plasma neutrophil gelatinase-associated lipocalin as a single test rule out biomarker for acute kidney injury: A cross-sectional study in patients admitted to the emergency department

André Torre, Lisbet Brandi, Jesper Juul Larsen, Thomas Kallemose et al.
2 citations
PLoS ONE
Acute Kidney Injury Research
2.86
article

Plasma neutrophil gelatinase-associated lipocalin as a single test rule out biomarker for acute kidney injury: A cross-sectional study in patients admitted to the emergency department

André Torre, Lisbet Brandi, Jesper Juul Larsen, Thomas Kallemose, Lennart Friis-Hansen, Martin Schultz, Vicky Jenny Rebecka Wetterstrand
article en
2 citations

Abstract

The study illustrates that the value of a single measurement of pNGAL is primarily in excluding AKI whereas it`s poorer in predicting the presence of AKI. When diagnosing AKI with pCr the optimal baseline pCr level is the mean of available pCr (mb-pCr) measurements from up to a year prior to the current event.

PLoS ONEVol. 20(1)
University of Copenhagen (DK), Herlev Hospital (DK), Hvidovre Hospital (DK), Copenhagen University Hospital (DK), Rigshospitalet (DK), Zealand University Hospital (DK)
BioPorto, Sjællands Universitetshospital
No poverty
Openalex Percentile: Top 13%
Acute Kidney Injury Research
2.86
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Plasma neutrophil gelatinase-associated lipocalin as a single test rule out biomarker for acute kidney injury: A cross-sectional study in patients admitted to the emergency department — André Torre, Lisbet Brandi, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS