Progress in Research on Mechanical Ventilation and Diaphragm Dysfunction

Mechanical ventilation is clinically used to assist in the gas exchange for patients who need to maintain adequate alveolar ventilation. Its common indications include respiratory failure, heart failure, drug overdose, and surgery. Although mechanical ventilation can save the lives of patients with respiratory failure, prolonged use can lead to diaphragm atrophy and contraction dysfunction. Currently, there is a lack of effective assessment and monitoring methods for diaphragm dysfunction in clinical practice, leading to insufficient attention to diaphragm function. Understanding the pathophysiological process of diaphragm dysfunction, assessment methods, and prevention and treatment strategies is crucial for improving the prognosis of ICU patients on mechanical ventilation. This paper briefly introduces the pathogenesis of diaphragm dysfunction, current assessment methods, and prevention and treatment strategies, hoping to provide some assistance to clinical practice.