Maternal X chromosome pericentric inversion resulting in the genetic analysis of offspring pedigrees with deletions at Xp22.33 and Xp22.33p11.3, and duplications at Xq27.3q28: Case report
Maternal X chromosome pericentric inversion significantly affects offspring genetic outcomes. Assisted reproductive technologies, including in vitro fertilization with preimplantation genetic testing, are recommended to reduce recurrence risks in future pregnancies. Prenatal genetic testing is advised for natural conception to ensure fetal genetic health.
Authors
- Zengyu Yang
- Derong Li (ORCID: https://orcid.org/0000-0002-7689-7921)
- Yudi Luo (ORCID: https://orcid.org/0000-0003-1943-5031)
- Guosheng Deng
- Bowen Luo (ORCID: https://orcid.org/0000-0003-1618-2980)
- Yi‐Ting Lai (ORCID: https://orcid.org/0000-0001-8631-3208)
- Keng Feng (ORCID: https://orcid.org/0009-0009-7472-5227)
- Ling‐Ling Zhu (ORCID: https://orcid.org/0000-0002-6474-5875)
- Xiang Li (ORCID: https://orcid.org/0009-0008-2830-0140)
Institutions
- Qinzhou Maternity and Child Health Care Hospital (CN)
- Jilin Maternity and Child Health Care Hospital (CN)
- Yulin Orthopedics Hospital of Chinese and Western Medicine (CN)
Publication Details
- Journal
- Medicine
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1097/md.0000000000041255
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.00