Malignant hypertension induces thrombotic microangiopathy and renal failure: A case report

TMA caused by malignant hypertension is rare and similar to the clinical manifestations of TMA caused by Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome, but it is often sudden and critical. Early identification and diagnosis and aggressive antihypertensive therapy, must be given to avoid end-stage renal disease, long-term maintenance of dialysis, and the financial burden of unnecessary plasmapheresis and potential side effects of glucocorticoids.

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Journal
Medicine
Published
2025-01-10
DOI
https://doi.org/10.1097/md.0000000000041186
Primary Topic
Complement system in diseases
Type
article
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article

Malignant hypertension induces thrombotic microangiopathy and renal failure: A case report

Youhua Xu, Xi Sun, Chunying Liu, HE Li-qun et al.
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Medicine
Complement system in diseases
article

Malignant hypertension induces thrombotic microangiopathy and renal failure: A case report

Youhua Xu, Xi Sun, Chunying Liu, HE Li-qun, Yanyun Ren
article en

Abstract

TMA caused by malignant hypertension is rare and similar to the clinical manifestations of TMA caused by Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome, but it is often sudden and critical. Early identification and diagnosis and aggressive antihypertensive therapy, must be given to avoid end-stage renal disease, long-term maintenance of dialysis, and the financial burden of unnecessary plasmapheresis and potential side effects of glucocorticoids.

MedicineVol. 104(2)
Macau University of Science and Technology (MO), Shanghai University of Traditional Chinese Medicine (CN), Affiliated Hospital of Shaanxi University of Chinese Medicine (CN), Shuguang Hospital (CN)
Good health and well-being
Openalex Percentile: Top 99%
Complement system in diseases
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Malignant hypertension induces thrombotic microangiopathy and renal failure: A case report — Youhua Xu, Xi Sun, et al. · Medicine (2025) | TGRS Research Map | TGRS