Bacillus coagulans alleviates hepatic injury caused by Klebsiella pneumoniae in rabbits
Above data indicate that BC supplementation effectively attenuated oxidative stress and inflammatory response induced by KP through augmenting the activities of antioxidant enzymes and diminishing the levels of pro-inflammatory factors. Furthermore, it reduced the Bax/Bcl-2 ratio in the liver, thereby inhibiting KP-induced apoptosis. The treatment group receiving 5x106 CFU/g BC benefitted most from the protective effect.
Authors
- Ziqiang Zhang (ORCID: https://orcid.org/0000-0003-3808-162X)
- Jianing Wang (ORCID: https://orcid.org/0000-0002-8064-8151)
- Xiao‐Guang Chen (ORCID: https://orcid.org/0000-0002-7927-691X)
- Yumei Liu (ORCID: https://orcid.org/0009-0004-5986-4943)
- Wendi Wei
- Qiongxia Lv
- Fan Yang (ORCID: https://orcid.org/0000-0002-8111-4880)
Institutions
- Henan University of Science and Technology (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1371/journal.pone.0317252
- Citations
- 1
- Primary Topic
- Rabbits: Nutrition, Reproduction, Health
- Type
- article
- Field-Weighted Citation Impact
- 1.19