3D Skull Completion via Two-stage Conditional Diffusion-Based Signed Distance Fields
A fast and fully automatic design of 3D cranial implants is highly desired in cranioplasty, and is key to the treatment of skull trauma. We have defined the repair of skull defects as a 3D shape completion task by proposing a two-stage diffusion model based on the representation of 3D shapes using signed distance function (SDF). Specifically, we design a diffusion model conditioned on partial shapes, we compress the 3D shape into a compact latent representation using the encoder in the vector quantized variational autoencoder (VQ-VAE) and learn the diffusion model based on this compressed discrete representation. Encoding the latent space with the autoencoder can achieve high-quality 3D cranial shape completion. In order to accurately capture local and fine-grained shape details, the training data is geometrically encoded from a compactly learned code-book. The two-stage diffusion generator with a coarse-to-fine approach possesses precise and expressive structural modeling capabilities to ensure the supplementation of detailed geometric information. Experimental results verified sufficient expressiveness of our model with generating high-fidelity results with fine-grained local details, outperforming the state-of-the-art methods.
Authors
- Xudong Ru (ORCID: https://orcid.org/0000-0003-1502-1712)
- Xingce Wang (ORCID: https://orcid.org/0000-0002-3177-8902)
- Chong Zhang (ORCID: https://orcid.org/0000-0003-0679-7623)
- Alejandro Federico Frangi (ORCID: https://orcid.org/0000-0002-2675-528X)
- Yi‐Cheng Zhu (ORCID: https://orcid.org/0000-0002-8966-1379)
- Zhenhong Liu (ORCID: https://orcid.org/0000-0002-8026-9629)
- Zhongke Wu (ORCID: https://orcid.org/0000-0003-3735-6476)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Normal University (CN)
- Peking Union Medical College Hospital (CN)
- University of Manchester (GB)
Publication Details
- Published
- 2024-12-03
- DOI
- https://doi.org/10.1109/bibm62325.2024.10822061
- Citations
- 2
- Primary Topic
- Medical Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.37
Funders
- Royal Academy of Engineering
- Beijing Municipal Science and Technology Commission
- Nature