Angiotensin-Receptor Blockers Prevent Vestibular Schwannoma–Associated Hearing Loss
This study represents the first statistically significant association between ARB intake and hearing preservation in a real-world VS patient population. Significant confounding factors, such as concomitant hypertension in these patients, could still cloud the full effect of ARB medications' interaction with SNHL progression. Given that ARBs are well tolerated and safe, the results advocate for a prospective clinical trial to validate this effect.
Authors
- Alyssa Brown
- Konstantina M. Stanković (ORCID: https://orcid.org/0000-0003-0233-279X)
- Samuel Early
- Lei Xu (ORCID: https://orcid.org/0000-0003-0525-183X)
Institutions
- Massachusetts Eye and Ear Infirmary (US)
- Harvard University (US)
- University of San Diego (US)
- Neurosciences Institute (US)
- University of California San Diego (US)
- Massachusetts General Hospital (US)
- Stanford Medicine (US)
- Stanford University (US)
Publication Details
- Journal
- Otology & Neurotology
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1097/mao.0000000000004376
- Citations
- 3
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Fondation Bertarelli
- National Institutes of Health