Fingolimod-associated cryptococcal meningitis in a patient with Multiple Sclerosis: A case report and literature review

A 65-year-old woman with Multiple Sclerosis treated with fingolimod developed headaches and convulsions. Cerebrospinal fluid (CSF) culture indicated <i>Cryptococcus neoformans</i>. A literature review of 20 cases of cryptococcal meningitis indicated that headache was the most common initial symptom, and all cases were positive for serum and/or CSF cryptococcal antigens.

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Publication Details

Journal
IDCases
Published
2025-01-01
DOI
https://doi.org/10.1016/j.idcr.2025.e02150
Primary Topic
Fungal Infections and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Fingolimod-associated cryptococcal meningitis in a patient with Multiple Sclerosis: A case report and literature review

Michinori Shirano, Takahiro Mitsueda, Hidenori Nakagawa, A Takagi
IDCases
Fungal Infections and Studies
article

Fingolimod-associated cryptococcal meningitis in a patient with Multiple Sclerosis: A case report and literature review

Michinori Shirano, Takahiro Mitsueda, Hidenori Nakagawa, A Takagi
article en

Abstract

A 65-year-old woman with Multiple Sclerosis treated with fingolimod developed headaches and convulsions. Cerebrospinal fluid (CSF) culture indicated <i>Cryptococcus neoformans</i>. A literature review of 20 cases of cryptococcal meningitis indicated that headache was the most common initial symptom, and all cases were positive for serum and/or CSF cryptococcal antigens.

IDCasesVol. 39
Osaka City General Hospital (JP)
Good health and well-being
Openalex Percentile: Top 99%
Fungal Infections and Studies
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