Giant T Waves to Recognize: About Two Cases

De Winter syndrome is a rare electrocardiographic pattern first described in 2008, representing an equivalent to ST-elevation myocardial infarction (STEMI) and indicative of acute proximal occlusion of the left anterior descending (LAD) artery.Despite its clinical significance, it remains underrecognized, leading to diagnostic delays and increased morbidity.We report two male patients with cardiovascular risk factors who presented with acute typical anginal pain and characteristic ECG findings of upward-sloping ST depression and prominent T waves.Coronary angiography confirmed critical proximal LAD occlusion, and immediate percutaneous coronary intervention (PCI) with drug-eluting stents resulted in significant clinical improvement.This report highlights the need for heightened clinical awareness and early recognition of this pattern to ensure timely reperfusion therapy and improve patient outcomes.