Recognizing Practice Gaps Schizophrenia Diagnosis and Treatment: Results of a CME Accredited Survey

Background Schizophrenia is a severe chronic illness that affects approximately 1% of the population worldwide and is estimated to affect at least 3.5 million people in the United States. Although a range of antipsychotic medications exists for treating schizophrenia, outcomes have historically been poor, and evidence confirms that clinicians remain challenged to individualize treatment for patients living with schizophrenia. This study was designed to understand the clinical practice gaps and perspectives of clinicians related to managing schizophrenia and help inform the development of education and tools to improve clinician knowledge, competence and confidence. Methods A survey instrument containing 24 multiple choice, knowledge and case-based questions was used to assess participants’ knowledge, attitudes, and confidence in the management of Schizophrenia. The survey was available online to US and global physicians without monetary compensation or charge. Respondent confidentiality was maintained, and the responses were de-identified and aggregated prior to analyses. Questions were grouped into clinical themes and analyzed. Data were collected from 8/11/2022 to 12/14/2022. Results In total, 560 psychiatrists, and 94 Primary Care Physicians answered all questions in the assessment. Physicians demonstrated gaps in the following areas: Correct Answer Clinical Theme Psychiatrists (n=560) Primary Care Physicians (n=94) Diagnosis and Assessment 54% 38% MOA of novel and emerging therapies 39% 32% Treatment nonresponse 67% 55% Individualizing treatment 50% 38% Conclusion This educational research on assessment of clinical practices revealed important knowledge and competence gaps amongst psychiatrists and PCPs who manage patients with Schizophrenia. Addressing these gaps is critical to improving the management of patients. Funding Medscape Education, Cerevel Therapeutics