Glycolysis Dictates Response to Fasting-Mimicking Diet in Breast Cancer

Major Finding: Fasting-mimicking diet plus chemotherapy exhibits high response rates in triple-negative breast cancer.Concept: Tumors of complete responders exhibit an early downregulation of glucose metabolism genes and pathways. Impact: Early downregulation of glycolysis may be a predictive biomarker of response to fasting-mimicking diets.

Publication Details

Journal
Cancer Discovery
Published
2025-01-01
DOI
https://doi.org/10.1158/2159-8290.cd-rw2025-004
Primary Topic
Nutrition, Genetics, and Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Glycolysis Dictates Response to Fasting-Mimicking Diet in Breast Cancer

Cancer Discovery
Nutrition, Genetics, and Disease
article

Glycolysis Dictates Response to Fasting-Mimicking Diet in Breast Cancer

article en

Abstract

Major Finding: Fasting-mimicking diet plus chemotherapy exhibits high response rates in triple-negative breast cancer.Concept: Tumors of complete responders exhibit an early downregulation of glucose metabolism genes and pathways. Impact: Early downregulation of glycolysis may be a predictive biomarker of response to fasting-mimicking diets.

Cancer Discovery
Zero hunger
Openalex Percentile: Top 99%
Nutrition, Genetics, and Disease
DOISourceOpenAlex
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Glycolysis Dictates Response to Fasting-Mimicking Diet in Breast Cancer · Cancer Discovery (2025) | TGRS Research Map | TGRS