Preparation and application of a Brucella multiepitope fusion protein based on bioinformatics and Tandem Mass Tag-based proteomics technology
A novel multiepitope fusion protein has been successfully developed utilizing bioinformatics and TMT proteomics technology. This fusion protein demonstrates significant potential as a diagnostic antigen for brucellosis, exhibiting high sensitivity and specificity.
Authors
- Meixue Yao
- Liping Guo (ORCID: https://orcid.org/0000-0003-2065-387X)
- Yuan Yuan (ORCID: https://orcid.org/0000-0001-6674-9848)
- Dehui Yin (ORCID: https://orcid.org/0000-0002-7164-9320)
- Yujia Xie (ORCID: https://orcid.org/0000-0003-2668-8272)
- Qi Wu (ORCID: https://orcid.org/0000-0003-3562-6129)
Institutions
- Jinan University (CN)
- Xuzhou Medical College (CN)
- Zhuhai People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-01-10
- DOI
- https://doi.org/10.3389/fimmu.2024.1509534
- Citations
- 4
- Primary Topic
- Brucella: diagnosis, epidemiology, treatment
- Type
- article
- Field-Weighted Citation Impact
- 9.42