Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion
Our research shows that inhibition SIRT1 can regulate Treg and Th17 immune balance axis. This finding indicates a new important potential target for the treatment of UC.
Authors
- Qingqing Yang (ORCID: https://orcid.org/0000-0002-0807-0551)
- Jun‐Meng Wang (ORCID: https://orcid.org/0000-0003-3771-4026)
- Yuemei Wang (ORCID: https://orcid.org/0000-0002-7975-1856)
- Qianhui Huang (ORCID: https://orcid.org/0000-0002-3292-7519)
- Yuanbing Zhu (ORCID: https://orcid.org/0000-0001-9792-2463)
- Xiaotong Zuo
- Lulu Cao (ORCID: https://orcid.org/0009-0000-0088-5919)
- Yan-ling Ping
- Qin Huang (ORCID: https://orcid.org/0000-0003-4139-3819)
- Shuqing Liu
- Mu-qiu Tian
- Qiao‐Feng Wu (ORCID: https://orcid.org/0000-0002-8870-6707)
Institutions
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-01-10
- DOI
- https://doi.org/10.3389/fimmu.2024.1525469
- Citations
- 8
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 6.45
Funders
- National Natural Science Foundation of China
- Department of Science and Technology of Sichuan Province