Multiomic analysis of lactylation and mitochondria-related genes in hepatocellular carcinoma identified MRPL3 as a new prognostic biomarker

We created a predictive model, LMRG, and identified MRPL3 as a key biomarker. Our findings suggest that MRPL3 has significant potential as a reliable predictive biomarker for clinical applications in HCC diagnosis and treatment.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-01-10
DOI
https://doi.org/10.3389/fonc.2024.1511958
Citations
6
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
Field-Weighted Citation Impact
5.62
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article

Multiomic analysis of lactylation and mitochondria-related genes in hepatocellular carcinoma identified MRPL3 as a new prognostic biomarker

Taiyang Zhu, Rongwei Shi, Shibing Cao, Qiuzi Long et al.
6 citations
Frontiers in Oncology
Cancer, Hypoxia, and Metabolism
5.62
article

Multiomic analysis of lactylation and mitochondria-related genes in hepatocellular carcinoma identified MRPL3 as a new prognostic biomarker

Taiyang Zhu, Rongwei Shi, Shibing Cao, Qiuzi Long, Gaoyuan Wang, Xiuxian Yin, Jinlong Huang, Wenge Xing, Yin Zhou, Yi Nan
article en
6 citations

Abstract

We created a predictive model, LMRG, and identified MRPL3 as a key biomarker. Our findings suggest that MRPL3 has significant potential as a reliable predictive biomarker for clinical applications in HCC diagnosis and treatment.

Frontiers in OncologyVol. 14
Nanjing University of Chinese Medicine (CN), Jiangsu Province Hospital (CN)
Good health and well-being
Openalex Percentile: Top 4%
Cancer, Hypoxia, and Metabolism
5.62
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