Geographical variation in metabolite profiles and bioactivity of Thesium chinense Turcz. revealed by UPLC-Q-TOF-MS-based metabolomics
A strong correlation was observed between metabolite content and geographical origins, suggesting that the bioactivity of TCT is significantly influenced by its provenance. Additionally, the antioxidant and anti-inflammatory activities of TCT were validated, showing a strong predictive relationship with TFC. This research highlights the potential of metabolomics in discerning the subtleties of plant metabolomes, contributing to the advancement of traditional Chinese medicine and its integration into modern healthcare practices.
Authors
- Tingting Sun (ORCID: https://orcid.org/0000-0002-8253-4000)
- Ke Che
- Fang Zhang (ORCID: https://orcid.org/0000-0002-1506-3384)
- Cong Wang (ORCID: https://orcid.org/0000-0002-4100-4222)
- Mengyuan Chen (ORCID: https://orcid.org/0009-0001-8155-0930)
- Hao Chen (ORCID: https://orcid.org/0009-0006-7836-0091)
- Qisheng Yao
- Haonan Xu
- Hao Yu (ORCID: https://orcid.org/0000-0002-6038-1883)
- Guanglei Zhang (ORCID: https://orcid.org/0000-0003-2986-7743)
- Youyi Xiong (ORCID: https://orcid.org/0000-0002-8810-1652)
- Niannian Zhou
Institutions
- Anhui University of Science and Technology (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Nanjing University of Science and Technology (CN)
- Anhui Science and Technology University (CN)
- Bozhou People's Hospital (CN)
- Hua Medicine (China) (CN)
Publication Details
- Journal
- Frontiers in Plant Science
- Published
- 2025-01-10
- DOI
- https://doi.org/10.3389/fpls.2024.1471729
- Citations
- 5
- Primary Topic
- Lipid metabolism and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 5.56
Funders
- Natural Science Foundation of Anhui Province