Blood Group B May Reduce Risk of Rebleeding in Patients With Upper Gastrointestinal Haemorrhage due to Peptic Ulcer Disease
Risk stratification tools for the prediction of complications in patients with upper gastrointestinal haemorrhage are crucial for appropriate management. Blood group status has been associated with the risk of bleeding, thrombosis and risk of peptic ulcer disease (PUD). We assessed the influence of blood group status on rebleeding and other complications in 699 patients with PUD bleeding. Blood group B was associated with reduced risk in the composite outcome of rebleeding, need for surgery or embolisation and mortality (OR 0.15, 95% CI 0.04-0.63, p = 0.009). Blood group B was protective against rebleeding compared to non-blood group B (OR 0.20, 95% CI 0.05-0.84, p = 0.028).
Authors
- Prahlad Ho (ORCID: https://orcid.org/0000-0003-1875-3927)
- Mark Tacey (ORCID: https://orcid.org/0000-0002-6318-3911)
- Ray Boyapati (ORCID: https://orcid.org/0000-0001-9683-8411)
- Peter G. Gibson (ORCID: https://orcid.org/0000-0001-5865-489X)
- Mayur Garg (ORCID: https://orcid.org/0000-0002-9149-3589)
- Ross Apostolov (ORCID: https://orcid.org/0000-0002-4827-8795)
- Anuk Kruavit
- Krishneel Dutt
- N.‐Y. Lee
- Lynna Chen (ORCID: https://orcid.org/0000-0002-2505-3657)
- Bei Ye (ORCID: https://orcid.org/0000-0002-5022-7954)
- Mani Suleiman (ORCID: https://orcid.org/0000-0002-5892-5095)
- Sim Ong
- Sarah Taylor
Institutions
- The University of Melbourne (AU)
- Northern Health (AU)
- Eastern Health (AU)
- Monash Health (AU)
- Melbourne Health (AU)
- Austin Health (AU)
- Monash University (AU)
Publication Details
- Journal
- Alimentary Pharmacology & Therapeutics
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1111/apt.18485
- Citations
- 1
- Primary Topic
- Gastrointestinal Bleeding Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.81