Sister Mary Joseph Nodule Found As a Cutaneous Manifestation of Metastatic Ovarian Carcinoma: A Case Report

Background: Sister Mary Joseph's nodule is a medical eponym used for a rare umbilical metastatic lesion presenting as a palpable nodule protruding into the umbilicus resulting from an advanced intra-abdominal and or pelvic malignancy.It is an uncommon but yet significant finding.Case Presentation: We report a 67-year-old woman with imaging findings of a metastatic right ovarian tumor with Sister Mary Joseph's nodule.A total abdominal hysterectomy with bilateral salpingo-oophorectomy, umbilical nodule, and infracolic omentum resections was performed and a histopathology diagnosis of bilateral low-grade ovarian serous papillary cystadenocarcinoma with metastases to the umbilicus and omentum was made.Conclusion: Sister Mary Joseph's nodule is a rare and often a poor prognostic sign of a disseminated intra-abdominal and or pelvic malignancy.There is a need to consider this lesion as a differential diagnosis of an advanced intra-abdominal and or pelvic malignancy.