Leucocytes and CD4 Counts of Individuals Exposed to Roadside Dust in Ekpoma, Edo State, Nigeria

Roadside dust is a combination of particulate matter generated from vehicular traffic and other human activities along the road.This study investigated the leucocytes and Cluster of Differentiation-4 (CD4) counts of individuals exposed to roadside dust in Ekpoma, Edo State.A total to 50 test subjects aged 18-65 years and of both sexes were recruited for this study, while 50 individuals not exposed to road-side dust served as controls.The leucocytes and CD4 counts were analyzed using Sysmex KX-21N Autoanalyzer and Flow cytometry method respectively.The results obtained revealed the total white blood cell counts of the subjects studied were 5.271.60 and 5.221.66 for the test and control subjects respectively.With respect to the differential leucocyte count, the mean values of the test and control subjects for NEUT %, LYM % and MXD % were 40.319.75 and 38.6210.0,47.9 9.15 and 50.79.86,11.664.40and 10.73.72 respectively.Furthermore, the mean values of the CD4 counts of the test and control subjects were 890.26266.21 and 850.94302.13respectively.Statistical comparison of the mean values of total WBC, differential leucocytes count and CD4 counts and road side dust did not reveal any significant difference (p>0.05).With respect to age, gender and duration of exposure to road-side dust, the leucocytes and CD4 counts were not significantly affected.In conclusion, exposure to road dust did not affect the leucocytes and CD4 counts of our study subjects.