Diagnosis and Treatment of Aspergillosis

Aspergillosis is an infection caused by the fungus Aspergillus , which typically affects individuals with weakened immune systems. One of the more serious forms of this infection is chronic pulmonary aspergillosis, which has a mortality rate of over 50%. This infection is estimated to affect approximately 3 million people worldwide, making it a significant global health issue. Accurate diagnosis and effective management are crucial to reducing morbidity and mortality. This article aims to explore the diagnosis and management of aspergillosis. The method employed is a literature review, with data obtained from various scientific articles through databases such as PubMed, Google Scholar, and ScienceDirect, with a publication limit of the last 10 years. Diagnosis of aspergillosis is based on clinical manifestations and supported by laboratory, radiological, and mycological examinations. Management of aspergillosis includes the administration of oral corticosteroids, antifungal drugs, surgery, and immunomodulatory therapy. Diagnosis is established based on clinical symptoms and relevant supporting examinations, while treatment is adjusted according to the severity of the infection and the patient's overall health condition. The conclusion of this article emphasizes the importance of early diagnosis and appropriate management in reducing the mortality rate associated with aspergillosis.

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Publication Details

Journal
JURNAL BIOLOGI TROPIS
Published
2024-10-16
DOI
https://doi.org/10.29303/jbt.v24i4.7682
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

Diagnosis and Treatment of Aspergillosis

Prima Belia Fathana, Baiq Fanindya Harliza
JURNAL BIOLOGI TROPIS
Antifungal resistance and susceptibility
article

Diagnosis and Treatment of Aspergillosis

Prima Belia Fathana, Baiq Fanindya Harliza
article en

Abstract

Aspergillosis is an infection caused by the fungus Aspergillus , which typically affects individuals with weakened immune systems. One of the more serious forms of this infection is chronic pulmonary aspergillosis, which has a mortality rate of over 50%. This infection is estimated to affect approximately 3 million people worldwide, making it a significant global health issue. Accurate diagnosis and effective management are crucial to reducing morbidity and mortality. This article aims to explore the diagnosis and management of aspergillosis. The method employed is a literature review, with data obtained from various scientific articles through databases such as PubMed, Google Scholar, and ScienceDirect, with a publication limit of the last 10 years. Diagnosis of aspergillosis is based on clinical manifestations and supported by laboratory, radiological, and mycological examinations. Management of aspergillosis includes the administration of oral corticosteroids, antifungal drugs, surgery, and immunomodulatory therapy. Diagnosis is established based on clinical symptoms and relevant supporting examinations, while treatment is adjusted according to the severity of the infection and the patient's overall health condition. The conclusion of this article emphasizes the importance of early diagnosis and appropriate management in reducing the mortality rate associated with aspergillosis.

JURNAL BIOLOGI TROPISVol. 24(4)
University of Mataram (ID)
Good health and well-being
Openalex Percentile: Top 69%
Antifungal resistance and susceptibility
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