Overexpression of HHLA2 and PD-L1 anticipates weak prognosis in esophageal cancer patients

Esophageal cancer is one of the most common leading causes of cancer-related mortality worldwide, its incidence has increased particularly in the last few decades in the Western world. Esophageal cancer also has a poor prognosis as it cannot be diagnosed until the advanced stages due to the shortage of early clinical symptoms.