KDM4A Silencing Reverses Cisplatin Resistance in Ovarian Cancer Cells by Reducing Mitophagy <i>via</i> SNCA Transcriptional Inactivation

Silencing of KDM4A-mediated transcription inactivation of SNCA reduces mitophagy, thus inhibiting the resistance of ovarian cancer cells to cisplatin. KDM4A may be a promising drug target for DDP-resistant ovarian cancer cells.

Authors

Huiqing Ding (ORCID: https://orcid.org/0000-0001-5175-3617)
Meiya Mao
Hongyan Shi (ORCID: https://orcid.org/0009-0002-4192-793X)
Yan Xing (ORCID: https://orcid.org/0000-0002-2744-5283)
Tianhong Zhu

Institutions

Ningbo University (CN)
Ningbo First Hospital (CN)

Publication Details

Journal: Current Molecular Medicine
Published: 2025-01-10
DOI: https://doi.org/10.2174/0115665240281083241112053145
Citations: 1
Primary Topic: Histone Deacetylase Inhibitors Research
Type: article
Field-Weighted Citation Impact: 0.81

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article

KDM4A Silencing Reverses Cisplatin Resistance in Ovarian Cancer Cells by Reducing Mitophagy via SNCA Transcriptional Inactivation

Huiqing Ding, Meiya Mao, Hongyan Shi, Yan Xing et al.

Jan 10, 2025

1 citations

Current Molecular Medicine

Histone Deacetylase Inhibitors Research

0.81

article

KDM4A Silencing Reverses Cisplatin Resistance in Ovarian Cancer Cells by Reducing Mitophagy via SNCA Transcriptional Inactivation

Huiqing Ding, Meiya Mao, Hongyan Shi, Yan Xing, Tianhong Zhu

January 10, 2025article en

1 citations

Abstract

Current Molecular MedicineVol. 25(11)

Ningbo University (CN), Ningbo First Hospital (CN)

Good health and well-being

Openalex Percentile: Top 32%

Histone Deacetylase Inhibitors Research

0.81

DOI Source OpenAlex

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KDM4A Silencing Reverses Cisplatin Resistance in Ovarian Cancer Cells by Reducing Mitophagy <i>via</i> SNCA Transcriptional Inactivation — Huiqing Ding, Meiya Mao, et al. · Current Molecular Medicine (2025) | TGRS Research Map | TGRS