Anti-neuroinflammatory and Neuroprotective Effects of T-006 on Alzheimer’s Disease Models by Modulating TLR4-Mediated MyD88/ NF-κB Signaling
T-006 inhibited TLR4-mediated MyD88/NF-κB signaling pathways to suppress neuroinflammation in the LPS-induced AD rat model.
Authors
- Jiehong Cheng
- Chunyan Yan (ORCID: https://orcid.org/0000-0002-9209-6630)
- Jiemei Zhou
- Guiliang Zhang (ORCID: https://orcid.org/0000-0003-0501-7533)
- Jieyu Xing (ORCID: https://orcid.org/0009-0008-9405-7847)
- Zheng Liu (ORCID: https://orcid.org/0000-0001-6952-3406)
- Haiyun Chen (ORCID: https://orcid.org/0000-0002-4673-9068)
- Xiao Chang (ORCID: https://orcid.org/0000-0001-5349-5498)
- Zaijun Zhang
Institutions
- Foshan University (CN)
- Jinan University (CN)
- Guangdong Pharmaceutical University (CN)
Publication Details
- Journal
- CNS & Neurological Disorders - Drug Targets
- Published
- 2025-01-10
- DOI
- https://doi.org/10.2174/0118715273337232241121113048
- Citations
- 5
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 4.21