Transdifferentiation of rat keratinocyte progenitors to corneal epithelial cells by limbal niche via the STAT3/PI3K/AKT signaling pathway
This study demonstrates the ability of LN to promote KPCs transdifferentiation into corneal epithelial cells in vitro, and this process is partially mediated by the STAT3/PI3K/AKT signaling pathway.
Authors
- Ming-Chang Zhang (ORCID: https://orcid.org/0009-0001-9112-0248)
- Hua-Tao Xie (ORCID: https://orcid.org/0000-0003-4027-691X)
- Yu-Ting Xiao (ORCID: https://orcid.org/0000-0002-0349-1699)
- Weixing Cai (ORCID: https://orcid.org/0000-0001-5506-7008)
- Chao Wang (ORCID: https://orcid.org/0000-0002-8054-3472)
- Yuzhi Li (ORCID: https://orcid.org/0000-0001-9062-8085)
- Xi Peng (ORCID: https://orcid.org/0000-0003-1898-9964)
- Jia-Song Wang
- Gong-Yue Wang
- Tian-Yu Yao (ORCID: https://orcid.org/0000-0002-9240-6395)
- Jiang-Lan Zhao
- Bei Wang
Institutions
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1186/s13287-024-04129-w
- Citations
- 2
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- National Natural Science Foundation of China
- Health and Family Planning Commission of Hubei Province
- Wuhan Union Hospital
- Key Technologies Research and Development Program
- Fundamental Research Funds for the Central Universities