Evaluating the Relationship between Cathepsins and Papillary Thyroid Carcinoma: A Mendelian Randomization Study
This study established a causal link between cathepsin levels and PTC risk, emphasizing the roles of cathepsin Z in its progression. These insights could lead to new therapeutic strategies targeting these enzymes. Further research is necessary to understand the underlying biological mechanisms and their clinical implications.
Authors
- Changwei Zhang (ORCID: https://orcid.org/0000-0002-7056-0711)
- Siyi Li (ORCID: https://orcid.org/0009-0001-9564-8840)
- Ling Jin (ORCID: https://orcid.org/0000-0003-3104-4439)
- Xiao Xiongsheng
- Zhi Zhang (ORCID: https://orcid.org/0009-0004-9018-1438)
- Liu Muge
- Chen Zhengde
- Chen Zhuoting
Institutions
- Guangdong Medical College (CN)
- Affiliated Hospital of Guangdong Medical College Hospital (CN)
Publication Details
- Journal
- Endocrine Metabolic & Immune Disorders - Drug Targets
- Published
- 2025-01-10
- DOI
- https://doi.org/10.2174/0118715303305715240912172648
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00