Systematic Characterization of the Chemical Constituents of in Vitro and in Vivo of Astragali Radix‐ <scp> <i>Salvia miltiorrhiza</i> </scp> Herb Pair by Ultra‐High‐Performance‐Liquid Chromatography‐Orbitrap Mass Spectrometry
A total of 142 components were identified in the extract of AR-SM. The cleavage patterns of flavonoids, terpenoids, phenolic acids, organic acids, saponins, and phenylpropanoids were summarized. Meanwhile, 89 compounds were tentatively identified in rat plasma, including 73 prototypes and 16 metabolites. The main metabolic pathways included oxidation, reduction, methylation, glucuronidation, and sulfation.
Authors
- Lexin Shu
- Huixin Qiu (ORCID: https://orcid.org/0000-0002-1467-2743)
- Shumin Zhang (ORCID: https://orcid.org/0000-0001-9529-7457)
- Yubo Li (ORCID: https://orcid.org/0000-0003-0455-0969)
- Sitong Liu (ORCID: https://orcid.org/0000-0001-6849-8704)
- Yanru Deng (ORCID: https://orcid.org/0000-0003-3177-7421)
- Jun Qian
- Qiduo Zhao
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1002/rcm.9977
- Citations
- 3
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 7.14
Funders
- National Natural Science Foundation of China