Urinary formic acid is associated with cerebral amyloid deposition and glucose metabolism in memory clinic patients
Urinary FA is associated with brain pathological changes in memory clinic patients, including cerebral Aβ deposition, glucose metabolism, white matter hyperintensities, and hippocampal atrophy. It could be used as a biomarker for the early diagnosis of AD and predicting Aβ deposition.
Authors
- Fengfeng Pan
- Fang Xie (ORCID: https://orcid.org/0000-0003-2667-281X)
- Liangying Zhu
- Liang Cui (ORCID: https://orcid.org/0000-0003-1112-6162)
- Qihao Guo (ORCID: https://orcid.org/0000-0001-5079-8047)
- Ying Wang (ORCID: https://orcid.org/0000-0003-2121-7025)
- Rongqiao He (ORCID: https://orcid.org/0000-0002-1087-6108)
- Yihui Guan (ORCID: https://orcid.org/0000-0002-2946-4293)
- Kun He (ORCID: https://orcid.org/0000-0002-6969-3488)
Institutions
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Sciences (CN)
- Fudan University (CN)
- Institute of Biophysics (CN)
- Shanghai Sixth People's Hospital (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1177/13872877241309117
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China