Application potential of ZnO nanoparticles in orthopedic

Orthopedic implants are susceptible to bacterial infections such as S. aureus and E. coli, which increase the risk of postoperative infection. Surface modification can effectively address this issue by imparting new properties to the implants without affecting their mechanical strength and Young's modulus. Zinc oxide nanoparticles have been widely studied due to their excellent bactericidal properties, osteogenic characteristics, and biological functions. The article aims to offer an extensive analysis of its bactericidal, cytocompatibility, and osteogenic advantages as well as potential limitations, and explore the feasibility of their application in orthopedic implants. It aims to provide new ideas and methods for solving implant-related infections and promoting bone repair.