Synthesis of some triazole and triazoline derivatives by green chemistry and study of their molecular docking with a study of them against anticancer and antifungal

In our research, we prepared derivatives of the triazole ring and triazoline by click chemistry method, and we identified the prepared compounds by spectroscopic methods, then the molecular fusion of these compounds was studied to find out the most likely compound associated with colonic cancer. The compound S2 shows the highest association with the protein responsible for the malignant cells, then we studied the biological activity. The compound M116 against colonic cancer cell show good results as an inhibitor of the studied cancer cell.