Intravenous administration of mitochondria improves ovarian function by anti-apoptosis in the premature ovarian insufficiency model
Tail vein injection of isolated mitochondria has the potential to enhance ovarian functions in an animal model of POI induced by cyclophosphamide, increase mitochondrial activity in impaired ovarian cells and decrease the rate of apoptosis.
Authors
- Yuanmei Wang (ORCID: https://orcid.org/0000-0002-5628-2276)
- Hanlin Yang (ORCID: https://orcid.org/0000-0003-3096-4882)
- Xing Zhao (ORCID: https://orcid.org/0000-0001-7399-3777)
- Dan Zi (ORCID: https://orcid.org/0000-0002-0778-9003)
- Hao Luo (ORCID: https://orcid.org/0000-0002-2321-9924)
- Qing Li (ORCID: https://orcid.org/0000-0002-2918-4945)
- Jun Tan (ORCID: https://orcid.org/0000-0001-6275-1326)
Institutions
- Guiyang Medical University (CN)
- Chongqing University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
- Ministry of Education (TH)
- Stem Cell Institute (PA)
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Climacteric
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1080/13697137.2024.2441248
- Citations
- 2
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 3.76
Funders
- National Natural Science Foundation of China
- Guizhou Science and Technology Department
- Ministry of Science and Technology, Government of the People’s Republic of Bangladesh
- Science and Technology Bureau, Guiyang Municipal Government
- Special Funds for the Basic Research and Development Program in the Central Non-profit Research Institutesof China