Associations between lifelong cognitive reserve, Alzheimer's disease-related plasma biomarkers, and cognitive function in dementia-free older adults: A population-based study
Greater composite CR, derived from the CR indicators across different stages of the lifespan, is associated with better cognitive function independent of AD-related plasma biomarkers, driven mainly by early-life educational attainment.
Authors
- Yifeng Du (ORCID: https://orcid.org/0000-0002-4672-6654)
- Yuanjing Li (ORCID: https://orcid.org/0000-0002-1525-5538)
- Jiafeng Wang (ORCID: https://orcid.org/0009-0003-2268-1249)
- Yiming Song (ORCID: https://orcid.org/0000-0003-3525-2358)
- Chengxuan Qiu (ORCID: https://orcid.org/0000-0003-1922-4912)
- Qiwei Dong
- Qinghua Zhang (ORCID: https://orcid.org/0000-0003-2668-2145)
- Lin Cong (ORCID: https://orcid.org/0009-0003-1278-1334)
- Xinyu Liu (ORCID: https://orcid.org/0000-0003-0854-8559)
- Yongxiang Wang (ORCID: https://orcid.org/0000-0002-8832-7301)
- Lin Song (ORCID: https://orcid.org/0000-0003-2175-8788)
- Xiaojuan Han
- Shi Tang
- Tingting Hou (ORCID: https://orcid.org/0000-0003-2614-8145)
- Yu Zhang (ORCID: https://orcid.org/0000-0001-8296-154X)
Institutions
- Shandong University (CN)
- Stockholm University (SE)
- Karolinska Institutet (SE)
- Shandong Provincial Hospital (CN)
- Swedish School of Sport and Health Sciences (SE)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1177/13872877241306448
- Citations
- 8
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 11.77
Funders
- National Natural Science Foundation of China
- Vetenskapsrådet
- Natural Science Foundation of Shandong Province
- Direktoratet for internasjonalisering og kvalitetsutvikling i høgare utdanning