Association of small vessel disease progression with longitudinal cognitive decline across mild cognitive impairment
The progression of CMB and WMH had an impact on cognitive decline in both CN and MCI groups, and lacunes progression only had an association with cognitive decline in the MCI group. Our study suggested that individual SVD markers may have a higher predictive value in longitudinal cognition compared with global SVD burden.
Authors
- Haiying Chen
- Xuemiao Zhao (ORCID: https://orcid.org/0000-0002-9548-2561)
- Yunjun Yang (ORCID: https://orcid.org/0000-0003-2080-2417)
- Mengying Yu (ORCID: https://orcid.org/0000-0002-8255-508X)
- Lixuan Chen (ORCID: https://orcid.org/0000-0002-0333-7990)
- Jingru Wang (ORCID: https://orcid.org/0009-0006-8683-1121)
- Asta Debora
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1177/13872877241305800
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Alzheimer's Disease Neuroimaging Initiative
- DoD Alzheimer's Disease Neuroimaging Initiative