Spindle Cell Lipoma of the Fourth Metatarsal: A Case Report

Spindle cell lipoma (SCL) is a rare subtype of lipoma that typically arises in the subcutaneous tissue of the posterior neck and shoulders, most commonly in middle-aged men, and only rarely occurs in the extremities. SCL typically presents as a well-circumscribed, firm mass composed of CD34-positive adipocytes mixed with bland spindle cells and ropy collagen fibers. We present the case of a 46-year-old man who came to the hospital for routine hemodialysis treatment, during which his physician discovered a mass on his left fourth metatarsal that had been slowly growing for the past five years. A subdermal soft tissue lesion (5.6 cm x 3.8 cm x 4.5 cm) was excised, and histological findings confirmed the diagnosis of SCL. This case reports a rare occurrence of SCL in the metatarsal and emphasizes the importance of distinguishing SCL from its malignant equivalents, particularly when it occurs in rare and unusual locations.

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Journal
Cureus
Published
2025-01-10
DOI
https://doi.org/10.7759/cureus.77220
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
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article

Spindle Cell Lipoma of the Fourth Metatarsal: A Case Report

Khalid Ahmed Moustafa, Slava Albaghli, Selim Sürer
Cureus
Sarcoma Diagnosis and Treatment
article

Spindle Cell Lipoma of the Fourth Metatarsal: A Case Report

Khalid Ahmed Moustafa, Slava Albaghli, Selim Sürer
article en

Abstract

Spindle cell lipoma (SCL) is a rare subtype of lipoma that typically arises in the subcutaneous tissue of the posterior neck and shoulders, most commonly in middle-aged men, and only rarely occurs in the extremities. SCL typically presents as a well-circumscribed, firm mass composed of CD34-positive adipocytes mixed with bland spindle cells and ropy collagen fibers. We present the case of a 46-year-old man who came to the hospital for routine hemodialysis treatment, during which his physician discovered a mass on his left fourth metatarsal that had been slowly growing for the past five years. A subdermal soft tissue lesion (5.6 cm x 3.8 cm x 4.5 cm) was excised, and histological findings confirmed the diagnosis of SCL. This case reports a rare occurrence of SCL in the metatarsal and emphasizes the importance of distinguishing SCL from its malignant equivalents, particularly when it occurs in rare and unusual locations.

CureusVol. 17(1)
King Saud Medical City (SA), Ankara Yıldırım Beyazıt University (TR)
Zero hunger
Openalex Percentile: Top 99%
Sarcoma Diagnosis and Treatment
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Spindle Cell Lipoma of the Fourth Metatarsal: A Case Report — Khalid Ahmed Moustafa, Slava Albaghli, et al. · Cureus (2025) | TGRS Research Map | TGRS