Neuroprotective Effect of Melatonin Loaded in Human Serum Albumin Nanoparticles Applied Subconjunctivally in a Retinal Degeneration Animal Model
Np-HSA-Mel effectively overcame ocular barriers, achieving greater neuroprotective efficacy at the retinal level. These findings highlight the synergistic potential of albumin and Mel in treating neurodegenerative ocular diseases, opening new perspectives for future therapies.
Authors
- Carolina del Valle Bessone (ORCID: https://orcid.org/0000-0003-0393-424X)
- José D. Luna (ORCID: https://orcid.org/0000-0002-4203-7667)
- Mario Eduardo Guido (ORCID: https://orcid.org/0000-0002-5485-4904)
- Daniela Alejandra Quinteros (ORCID: https://orcid.org/0000-0001-7459-7442)
- Maximiliano N. Ríos (ORCID: https://orcid.org/0000-0003-3692-6553)
- Ayelén Inda
- Sofía Mickaela Martinez (ORCID: https://orcid.org/0000-0003-4146-180X)
- Daniel A. Allemandi (ORCID: https://orcid.org/0000-0003-0449-0302)
- Abril Bruera Bossio
Institutions
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Universidad Nacional de Córdoba (AR)
- National University of Villa María (AR)
- Research Centre in Biological Chemistry of Córdoba (AR)
- Hospital Privado (AR)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2025-01-10
- DOI
- https://doi.org/10.3390/pharmaceutics17010085
- Citations
- 2
- Primary Topic
- Circadian rhythm and melatonin
- Type
- article
- Field-Weighted Citation Impact
- 1.83
Funders
- Universidad Nacional de Córdoba
- Consejo Nacional de Investigaciones Científicas y Técnicas
- Fondo para la Investigación Científica y Tecnológica