Patient-derived cornea organoid model to study metabolomic characterization of rare disease: aniridia-associated keratopathy
This study emphasizes the profound impact of AAK mutations on metabolism, particularly in amino acid biosynthesis and energy metabolism pathways.
Authors
- Emirhan Nemutlu (ORCID: https://orcid.org/0000-0002-7337-6215)
- Sinan Güven (ORCID: https://orcid.org/0000-0001-5212-5516)
- Vedat Sarı (ORCID: https://orcid.org/0000-0002-3891-5869)
- Tuba Reçber (ORCID: https://orcid.org/0000-0001-8257-7628)
- Daniel Aberdam (ORCID: https://orcid.org/0000-0002-4019-5418)
- Ali Can Koç (ORCID: https://orcid.org/0000-0003-2481-7026)
- Gamze Koçak (ORCID: https://orcid.org/0000-0003-1164-367X)
Institutions
- Izmir University (TR)
- Inserm (FR)
- Dokuz Eylül University (TR)
- Université Paris Cité (FR)
- Sorbonne Paris Cité (FR)
- Centre de Recherche des Cordeliers (FR)
- Hacettepe University (TR)
Publication Details
- Journal
- BMC Ophthalmology
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1186/s12886-024-03831-w
- Citations
- 3
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.08
Funders
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu