Smartphone based non invasive real time white blood cell counter leveraging blue light and static magnetic field

White blood cells (WBCs), also known as leukocytes, are one of the most significant parts of the immune system. They generate antibodies, protect the body from illnesses, and heal wounds. Accurate estimation of WBCs is key for diagnosing cancer, infections, leukemia, lymphoma, and other diseases. However, the widely used Complete Blood Count (CBC) test presents challenges, including prick anxiety, discomfort, and logistical inconvenience to patients. This study introduces a ubiquous White Blood Cell counting system, UbiWhite, a novel smartphone-based, non-invasive system for real-time WBC counting from fingertip videos. Our system uses optical and magnetic techniques to provide accurate WBC counts without blood extraction. An initial experimentation was carried out on 20 adult participants to verify the system's effectiveness compared to standard CBC tests (IRB #4051). The developed algorithms exhibit 1.04 and 1.23 RMSE, respectively. Our innovation provides an easy, affordable, and instantaneous solution for monitoring WBCs in various healthcare settings, including homes and critical care units. Additionally, it serves as a beacon of hope for low- and middle-income nations, where access to and affordability of traditional lab tests are limited.

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Publication Details

Journal
Scientific Reports
Published
2025-01-10
DOI
https://doi.org/10.1038/s41598-024-81459-y
Citations
2
Primary Topic
Digital Imaging for Blood Diseases
Type
article
Field-Weighted Citation Impact
2.55

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article

Smartphone based non invasive real time white blood cell counter leveraging blue light and static magnetic field

Masud Rabbani, Kazi Shafiul Alam, Sheikh Iqbal Ahamed, Nafi Us Sabbir Sabith
2 citations
Scientific Reports
Digital Imaging for Blood Diseases
2.55
article

Smartphone based non invasive real time white blood cell counter leveraging blue light and static magnetic field

Masud Rabbani, Kazi Shafiul Alam, Sheikh Iqbal Ahamed, Nafi Us Sabbir Sabith
article en
2 citations

Abstract

White blood cells (WBCs), also known as leukocytes, are one of the most significant parts of the immune system. They generate antibodies, protect the body from illnesses, and heal wounds. Accurate estimation of WBCs is key for diagnosing cancer, infections, leukemia, lymphoma, and other diseases. However, the widely used Complete Blood Count (CBC) test presents challenges, including prick anxiety, discomfort, and logistical inconvenience to patients. This study introduces a ubiquous White Blood Cell counting system, UbiWhite, a novel smartphone-based, non-invasive system for real-time WBC counting from fingertip videos. Our system uses optical and magnetic techniques to provide accurate WBC counts without blood extraction. An initial experimentation was carried out on 20 adult participants to verify the system's effectiveness compared to standard CBC tests (IRB #4051). The developed algorithms exhibit 1.04 and 1.23 RMSE, respectively. Our innovation provides an easy, affordable, and instantaneous solution for monitoring WBCs in various healthcare settings, including homes and critical care units. Additionally, it serves as a beacon of hope for low- and middle-income nations, where access to and affordability of traditional lab tests are limited.

Scientific ReportsVol. 15(1)
Marquette University (US)
Marquette University
Openalex Percentile: Top 13%
Digital Imaging for Blood Diseases
2.55
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