Genetic Assessment of Living Kidney Transplant Donors: A Survey of Canadian Practices

Canadian transplant centers follow a case-by-case approach rather than a standard protocol for genetic assessment of LKDs given that current guideline recommendations are based on expert opinion due to a lack of a reliable body of evidence. With the expected rise in utilization of the increasingly available genetic testing, early multidisciplinary assessment including medical geneticists has the potential to improve personalized management. Studies examining long-term donor and graft outcomes are needed to construct the basis for evidence-based recommendations and inform the safety of donations.

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Publication Details

Journal
Canadian Journal of Kidney Health and Disease
Published
2025-01-10
DOI
https://doi.org/10.1177/20543581241293200
Citations
2
Primary Topic
Organ Donation and Transplantation
Type
article
Field-Weighted Citation Impact
3.76
Controls
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article

Genetic Assessment of Living Kidney Transplant Donors: A Survey of Canadian Practices

Thomas M. Kitzler, Somaya Zahran, Aisha Adil, Ahsan Alam et al.
2 citations
Canadian Journal of Kidney Health and Disease
Organ Donation and Transplantation
3.76
article

Genetic Assessment of Living Kidney Transplant Donors: A Survey of Canadian Practices

Thomas M. Kitzler, Somaya Zahran, Aisha Adil, Ahsan Alam, Ke Fan Bei, P. D. Okoh
article en
2 citations

Abstract

Canadian transplant centers follow a case-by-case approach rather than a standard protocol for genetic assessment of LKDs given that current guideline recommendations are based on expert opinion due to a lack of a reliable body of evidence. With the expected rise in utilization of the increasingly available genetic testing, early multidisciplinary assessment including medical geneticists has the potential to improve personalized management. Studies examining long-term donor and graft outcomes are needed to construct the basis for evidence-based recommendations and inform the safety of donations.

Canadian Journal of Kidney Health and DiseaseVol. 12
University Health Network (CA), University of Toronto (CA), McGill University Health Centre (CA), Toronto General Hospital (CA), Translational Research in Oncology (CA), McGill University (CA)
Good health and well-being
Openalex Percentile: Top 10%
Organ Donation and Transplantation
3.76
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Genetic Assessment of Living Kidney Transplant Donors: A Survey of Canadian Practices — Thomas M. Kitzler, Somaya Zahran, et al. · Canadian Journal of Kidney Health and Disease (2025) | TGRS Research Map | TGRS