Berberine Inhibits the Disruption of the Blood–Brain Barrier and Glial Cell Activation in a Rat Model of Acute Hepatic Encephalopathy
These findings suggest that BBR alleviates behavioural and molecular abnormalities in HE through NLRP3 inflammasome inhibition, highlighting its potential as a therapeutic agent for managing HE.
Authors
- Ashok Kumar Datusalia (ORCID: https://orcid.org/0000-0002-7499-1658)
- Syed Afroz Ali
Institutions
- National Institute of Pharmaceutical Education and Research (IN)
Publication Details
- Journal
- Phytotherapy Research
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1002/ptr.8430
- Citations
- 7
- Primary Topic
- Berberine and alkaloids research
- Type
- article
- Field-Weighted Citation Impact
- 9.76
Funders
- Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, India
- National Institute of Pharmaceutical Education and Research, Raebareli