Immune Cells and Intracerebral Hemorrhage: A Causal Investigation Through Mendelian Randomization
Our research provides robust evidence substantiating the causal relationship between specific immunophenotypes and ICH risk. The identification of these findings significantly enhances our understanding of the pathogenic mechanisms underlying ICH, particularly pertaining to the immune system. This breakthrough paves the way for innovative clinical and pharmaceutical research opportunities, potentially promoting the development of targeted therapies and enhanced strategies for managing and preventing ICH.
Authors
- Liumei Mo
- Wei Pan (ORCID: https://orcid.org/0000-0002-1159-0582)
- Kui Wang (ORCID: https://orcid.org/0000-0001-9610-8689)
- Lian Huang (ORCID: https://orcid.org/0000-0002-0416-7532)
- Wenjing Cao (ORCID: https://orcid.org/0000-0002-3488-2430)
Institutions
- Shandong University (CN)
- Foshan Maternity and Child Health Care Hospital (CN)
- First Affiliated Hospital of Jinan University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/brb3.70263
- Citations
- 7
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 9.72
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province