Metabolic Status and Hypertension: The Impact of Insulin Resistance-Related Indices on Blood Pressure Regulation and Hypertension Risk

Elevated levels of the insulin resistance indices TyG index, METS-IR, TG/HDL-C, and HOMA-IR are closely associated with hypertension risk. These indices can serve as effective markers for monitoring hypertension risk in clinical practice. However, larger-scale prospective cohort studies are needed to validate these findings and further explore the clinical application potential of the TyG index, METS-IR, TG/HDL-C, and HOMA-IR as tools for cardiovascular risk assessment. Such studies will help elucidate the specific causal relationships between these insulin resistance-related indices and hypertension and advance their practical application in clinical settings.

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Publication Details

Journal
Journal of the American Nutrition Association
Published
2025-01-10
DOI
https://doi.org/10.1080/27697061.2025.2450711
Citations
7
Primary Topic
Blood Pressure and Hypertension Studies
Type
article
Field-Weighted Citation Impact
9.72

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article

Metabolic Status and Hypertension: The Impact of Insulin Resistance-Related Indices on Blood Pressure Regulation and Hypertension Risk

Xinying Hu, Peng Han, Yong Liu
7 citations
Journal of the American Nutrition Association
Blood Pressure and Hypertension Studies
9.72
article

Metabolic Status and Hypertension: The Impact of Insulin Resistance-Related Indices on Blood Pressure Regulation and Hypertension Risk

Xinying Hu, Peng Han, Yong Liu
article en
7 citations

Abstract

Elevated levels of the insulin resistance indices TyG index, METS-IR, TG/HDL-C, and HOMA-IR are closely associated with hypertension risk. These indices can serve as effective markers for monitoring hypertension risk in clinical practice. However, larger-scale prospective cohort studies are needed to validate these findings and further explore the clinical application potential of the TyG index, METS-IR, TG/HDL-C, and HOMA-IR as tools for cardiovascular risk assessment. Such studies will help elucidate the specific causal relationships between these insulin resistance-related indices and hypertension and advance their practical application in clinical settings.

Journal of the American Nutrition AssociationVol. 44(6)
Heilongjiang University of Chinese Medicine (CN), First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
Heilongjiang Provincial Postdoctoral Science Foundation
Good health and well-being
Openalex Percentile: Top 2%
Blood Pressure and Hypertension Studies
9.72
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Metabolic Status and Hypertension: The Impact of Insulin Resistance-Related Indices on Blood Pressure Regulation and Hypertension Risk — Xinying Hu, Peng Han, et al. · Journal of the American Nutrition Association (2025) | TGRS Research Map | TGRS