Analysis of the Endocrine Responses to Anti-Diabetes Drugs: An Issue of Elevated Plasma Renin Concentration in Sodium-Glucose Co-Transporter 2 Inhibitor

SGLT2i was the only class of anti-diabetes drugs independently associated with elevated renin levels, with results similar to RAAS blockade and diuretics. Although SGLT2i appears to protect reno- and cardio-function, the clinical impact of increased renin warrants further precise study for verification.

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Publication Details

Journal
International Journal of General Medicine
Published
2025-01-01
DOI
https://doi.org/10.2147/ijgm.s497664
Primary Topic
Diabetes Treatment and Management
Type
article
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article

Analysis of the Endocrine Responses to Anti-Diabetes Drugs: An Issue of Elevated Plasma Renin Concentration in Sodium-Glucose Co-Transporter 2 Inhibitor

Shih‐Yuan Hung, I-Wen Chen, Cheng-Wei Lin
International Journal of General Medicine
Diabetes Treatment and Management
article

Analysis of the Endocrine Responses to Anti-Diabetes Drugs: An Issue of Elevated Plasma Renin Concentration in Sodium-Glucose Co-Transporter 2 Inhibitor

Shih‐Yuan Hung, I-Wen Chen, Cheng-Wei Lin
article en

Abstract

SGLT2i was the only class of anti-diabetes drugs independently associated with elevated renin levels, with results similar to RAAS blockade and diuretics. Although SGLT2i appears to protect reno- and cardio-function, the clinical impact of increased renin warrants further precise study for verification.

International Journal of General MedicineVol. Volume 18
Chang Gung University (TW), National Tsing Hua University (TW), Linkou Chang Gung Memorial Hospital (TW)
Good health and well-being
Openalex Percentile: Top 99%
Diabetes Treatment and Management
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