The M1/M2 Macrophage Polarization and Hepatoprotective Activity of Quercetin in Cyclophosphamide‐Induced Experimental Liver Toxicity
This study indicates that QUE has the potential to downregulate CTX-induced hepatic injury and regulate M1/M2 macrophage polarization to the M2 side, which indirectly demonstrates activation of anti-inflammatory signalling and tissue repair.
Authors
- Sevgi İrtegün Kandemir (ORCID: https://orcid.org/0000-0001-6160-5626)
- Uğur Şeker (ORCID: https://orcid.org/0000-0002-1693-6378)
- Gül Şahika Gökdemir (ORCID: https://orcid.org/0000-0002-8691-1504)
- Deniz Evrim Kavak (ORCID: https://orcid.org/0000-0002-9681-4468)
- Emre Uyar (ORCID: https://orcid.org/0000-0001-9941-1237)
Institutions
- Dicle University (TR)
- Üsküdar University (TR)
- Dokuz Eylül University (TR)
- Mardin Artuklu University (TR)
Publication Details
- Journal
- Veterinary Medicine and Science
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/vms3.70183
- Citations
- 6
- Primary Topic
- Chemotherapy-induced organ toxicity mitigation
- Type
- article
- Field-Weighted Citation Impact
- 8.83