Identification of therapeutic target genes for age-related hearing loss through systematic genome-wide mendelian randomization of druggable genes
Our findings identified 14 potential drug targets for ARHL. These findings offer promising leads for more effective treatments for ARHL and help determine the priority of drug development, potentially reducing costs.
Authors
- Ruru Qiao
- Bo Hou (ORCID: https://orcid.org/0000-0001-9918-8223)
- Tao Yan (ORCID: https://orcid.org/0000-0001-6919-7962)
- Kun Zhang (ORCID: https://orcid.org/0000-0001-6435-5386)
- Xinbo Xu (ORCID: https://orcid.org/0000-0003-0588-9104)
- Peng Qu (ORCID: https://orcid.org/0009-0003-6108-8384)
- Hanbing Zhang (ORCID: https://orcid.org/0000-0003-4987-932X)
Institutions
- Qilu Hospital of Shandong University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Experimental Gerontology
- Published
- 2025-01-10
- DOI
- https://doi.org/10.1016/j.exger.2025.112676
- Citations
- 1
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 1.46
Funders
- Natural Science Foundation of Shandong Province