Comorbidities Associated With Different Degrees of Severity in Children and Young People Hospitalized With Acute COVID-19
In this prospective cohort study with 2326 hospitalized children and young people with coronavirus disease 2019 in Spain and Colombia, 36.4% had comorbidities. Asthma, recurrent wheezing, chronic neurological, cardiac and pulmonary diseases significantly increased the risk of severe outcomes such as death, mechanical ventilation and intensive care unit admission. The incremental risk with additional comorbidities underscores the importance of targeted vaccination strategies for vulnerable children and young people populations.
Authors
- Carlos Grasa (ORCID: https://orcid.org/0000-0002-9323-2024)
- Sara Domínguez‐Rodríguez (ORCID: https://orcid.org/0000-0003-3747-9265)
- Álvaro Ballesteros (ORCID: https://orcid.org/0009-0001-4403-1023)
- Cinta Moraleda (ORCID: https://orcid.org/0000-0002-8335-903X)
- Antoni Soriano‐Arandes (ORCID: https://orcid.org/0000-0001-9613-7228)
- Carlo Giaquinto (ORCID: https://orcid.org/0000-0001-9365-0413)
- Cristina Epalza (ORCID: https://orcid.org/0000-0002-6929-4903)
- Alfredo Tagarro (ORCID: https://orcid.org/0000-0003-2860-3455)
- Andrea Ramírez Varela (ORCID: https://orcid.org/0000-0003-2685-9617)
- Charlotte Jackson (ORCID: https://orcid.org/0000-0001-8544-7685)
- Carlos Álvarez (ORCID: https://orcid.org/0000-0001-5419-4494)
- María Lucía Mesa
- Marthe Le Prevost (ORCID: https://orcid.org/0000-0001-5505-9809)
- Pablo Vásquez‐Hoyos (ORCID: https://orcid.org/0000-0002-4892-5032)
- Irati Gastesi (ORCID: https://orcid.org/0009-0006-8566-8430)
Institutions
- University of Padua (IT)
- Universidad de Los Andes (CO)
- Hospital Universitario La Paz (ES)
- Universidad Nacional de Colombia (CO)
- Research Institute Hospital 12 de Octubre (ES)
- PENTA Foundation (IT)
- Hospital Universitario 12 De Octubre (ES)
- Vall d'Hebron Institut de Recerca (ES)
- Centro de Investigación Biomédica en Red (ES)
- Madrid Health Service (ES)
- Hospital Universitario Infanta Sofía (ES)
- Fundación Universitaria Sanitas (CO)
- University College London (GB)
- Medical Research Council (GB)
- Universidad Europea de Madrid (ES)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1097/inf.0000000000004684
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00