Complete Genome Characterization of Canine Adenovirus From Türkiye With Next‐Generation Sequencing
The complete CAdV-2 genome sequence obtained in the present study is the first sequence from Europe. Comparative analysis with other genomes revealed some unique mutations. This study is the first to report the E250K amino acid change in the E3 ORFA gene in Türkiye. We anticipate that this data can be used in future CAdV-2 vaccine development studies. Further studies are recommended to evaluate the impact of these mutations on viral tropism and other host interactions.
Authors
- Mehmet Cevat Temizkan (ORCID: https://orcid.org/0000-0002-4353-6759)
- Secil Sevinc Temizkan (ORCID: https://orcid.org/0000-0002-2427-3877)
Publication Details
- Journal
- Veterinary Medicine and Science
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/vms3.70163
- Citations
- 1
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Sivas Cumhuriyet Üniversitesi