Variations and Opportunities in Postnatal Management of Hemolytic Disease of the Fetus and Newborn

In this cohort study of neonates with HDFN managed at 31 centers in 22 countries, significant practice variations in the postnatal management of HDFN were identified, highlighting the lack of, and need for, consensus. The study suggests that there is a potential beneficial clinical association of waiting for delivery until after 37 weeks and 0 days with frequency of exchange transfusions among neonates with HDFN. The framework to implement international guidelines is provided.

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Publication Details

Journal
JAMA Network Open
Published
2025-01-10
DOI
https://doi.org/10.1001/jamanetworkopen.2024.54330
Citations
11
Primary Topic
Neonatal Health and Biochemistry
Type
article
Field-Weighted Citation Impact
38.44
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article

Variations and Opportunities in Postnatal Management of Hemolytic Disease of the Fetus and Newborn

Ángel Guillermo Alcázar Grisi, Kamini Raghuram, María José Garcia Borau, Beate Mayer et al.
11 citations
JAMA Network Open
Neonatal Health and Biochemistry
38.44
article

Variations and Opportunities in Postnatal Management of Hemolytic Disease of the Fetus and Newborn

Ángel Guillermo Alcázar Grisi, Kamini Raghuram, María José Garcia Borau, Beate Mayer, Johannes Keunen, Baptiste Teillet, Louise Ghesquière, Greg Ryan, Borna Poljak, Fangbiao Tao, Wing Ting Tse, Paul DL Maurice, M. Cabrera, E. Antolín, Philipp Klaritsch, Olav Bjørn Petersen, Thameur Rakza, E. J. T. Verweij, Jessica Brayley, Rob Negrine, Annegret Geipel, Yoav Yinon, Kajsa Bohlin, Roland Devlieger, Asma Khalil, David Mackin, Eleonor Tiblad, Marie-Gabrielle Guillemin, Masja de Haas, Fergal D. Malone, Kerry Rademan, Gonzalo Mariani, Arturo Alejandro Canul-Euan, J Blank, Jana Lozar Krivec, Rahel Schuler, Agnès Mailloux, Johanna G. van der Bom, Tzipora Strauss, Joana Nunes, Maria Sanchez-Holgado, Derek de Winter, Enrico Lopriore, Aurora Viejo Llorente, Matthew A. Saxonhouse, E. Thorup, Johanna Rath, Stav Cohen, Kévin Le Duc, Christof Dame, C. Pacheco, Jiang-Qin Liu, Ziju Elanjikal, Ngina Connors, Anne Debeer, Francesco Cavigioli, R Axt-Fliedner, L. Geerts, Lizelle van Wyk, Karin Sundberg, Leandro Daniel Burgos Pratx, Gerhard Pichler, Frederik Banch Clausen, Edmond N. Kelly, Andrea Lampland, Alexander Hohnecker, Henrique Soares, James Castleman, Daniel Pfurtscheller, Niklas Thon, Sarah Verbeeck, Sílvia Colombo, Mihaela Rus, Chiara Nava, Mark D. Kilby, María F Galletti, Marcella Martins de Vasconcelos Vaena, Ivonne Bedei, Smriti Prasad, Liesbeth Lewi, Ming Zhou, Alexandra Matias, A Wolter, Aneta Soltirovska-Šalamon, Maria Cristina Santos, Leah Leibovitch, Francesca Castoldi, Jean‐Marie Jouannic, Stefan Verlohren, N H Segura Méndez, Maria Elisabeth Lopes Moreira, Elisenda Moliner Calderón, Iris Hellsing, Erika Hrastar, Raigam Jafet Martine-Portilla, Jose A. Montoya-Martinez
article en
11 citations

Abstract

In this cohort study of neonates with HDFN managed at 31 centers in 22 countries, significant practice variations in the postnatal management of HDFN were identified, highlighting the lack of, and need for, consensus. The study suggests that there is a potential beneficial clinical association of waiting for delivery until after 37 weeks and 0 days with frequency of exchange transfusions among neonates with HDFN. The framework to implement international guidelines is provided.

JAMA Network OpenVol. 8(1)
University of Copenhagen (DK), Mount Sinai Hospital (CA), Royal Women's Hospital (AU), Karolinska University Hospital (SE), Royal College of Surgeons in Ireland (IE), University of Liverpool (GB), University of Ljubljana (SI), Tel Aviv University (IL), St George's, University of London (GB), Chinese University of Hong Kong (HK), Universidade do Porto (PT), University of Toronto (CA), University of Milan (IT), Justus-Liebig-Universität Gießen (DE), Medical University of Graz (AT), Université de Lille (FR), Stellenbosch University (ZA), Rotunda Hospital (IE), University Hospital Bonn (DE), Sheba Medical Center (IL), Leiden University Medical Center (NL), Hospital Universitario La Paz (ES), Ljubljana University Medical Centre (SI), Hospital de Sant Pau (ES), Carolinas Medical Center (US), Hospital Italiano de Buenos Aires (AR), Copenhagen University Hospital (DK), Tygerberg Hospital (ZA), Rigshospitalet (DK), Karolinska Institutet (SE), Centre Hospitalier Universitaire de Lille (FR), Sanquin (NL), Sorbonne Université (FR), Hôpital Armand-Trousseau (FR), Instituto Nacional de Perinatología (MX), Liverpool Women's Hospital (GB), Assistance Publique – Hôpitaux de Paris (FR), Hôpital Saint-Antoine (FR), Administração Regional de Saúde de Lisboa e Vale do Tejo (PT), Centro de Información y Desarrollo de la Mujer (BO), St George's Hospital (GB), München Klinik (DE), Levine Children's Hospital (US), Children's Minnesota (US), Centre de Recherche Saint-Antoine (FR), Shanghai First Maternity and Infant Hospital (CN), Birmingham Women’s and Children’s NHS Foundation Trust (GB), Universidad Hospital Italiano (AR), Wake Forest University (US), Charité - Universitätsmedizin Berlin (DE), Umeå University (SE), KU Leuven (BE)
Good health and well-being
Openalex Percentile: Top 0%
Neonatal Health and Biochemistry
38.44
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