Establishing a living biobank of pediatric high-grade glioma and ependymoma suitable for cancer pharmacology

Hence, we describe a fast and robust process to biobank PDT-O for pediatric glial brain tumors. These PDT-O models have the potential for patient-specific modeling even after long-term expansion in vitro, and we established the proof-of-concept of their usefulness to support powerful preclinical studies.

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Institutions

Publication Details

Journal
Neuro-Oncology
Published
2025-01-09
DOI
https://doi.org/10.1093/neuonc/noaf007
Citations
7
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
11.38

Funders

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article

Establishing a living biobank of pediatric high-grade glioma and ependymoma suitable for cancer pharmacology

Claire Coquet, Arthur Tourbez, Luca Tiberi, Laura Broutier et al.
7 citations
Neuro-Oncology
Glioma Diagnosis and Treatment
11.38
article

Establishing a living biobank of pediatric high-grade glioma and ependymoma suitable for cancer pharmacology

Claire Coquet, Arthur Tourbez, Luca Tiberi, Laura Broutier, David Meyronet, Clara Savary, Laurent Clavier, Marc Barritault, Federico Di Rocco, Isabelle Rochet, Martine Cordier–Bussat, Alexandre Vasiljevic, Marie Castets, Hermes Paraqindes, Maud Hamadou, Swann Meyer, Thomas Diot, Jean‐Yves Blay, Clémence Deligne, Matteo Gianesello, Marjorie Carrère, Nicolas Gadot, Armin Curt, Alexandru Szathmári, Valéry Attignon, Virginie Marcel, Aurélie Dutour, P.A. Beuriat, Marc Billaud, Clément Berthelot, Julia Tomine, Pierre Leblond, J. Engel, C Bocquet, Flavie Bénard
article en
7 citations

Abstract

Hence, we describe a fast and robust process to biobank PDT-O for pediatric glial brain tumors. These PDT-O models have the potential for patient-specific modeling even after long-term expansion in vitro, and we established the proof-of-concept of their usefulness to support powerful preclinical studies.

Neuro-OncologyVol. 27(5)
Université Claude Bernard Lyon 1 (FR), Centre National de la Recherche Scientifique (FR), Inserm (FR), Hôpital Femme Mère Enfant (FR), Institut d’Hématologie et d’Oncologie Pédiatrique (FR), Hospices Civils de Lyon (FR), Centre Léon Bérard (FR), Centre de Recherche en Cancérologie de Lyon (FR), Dana-Farber/Harvard Cancer Center (US)
Société Française de lutte contre les Cancers et les leucémies de l'Enfant et de l'Adolescent, Agence Nationale de la Recherche, Fondation ARC pour la Recherche sur le Cancer, Ligue Contre le Cancer, LabEx DEvweCAN
Good health and well-being
Openalex Percentile: Top 2%
Glioma Diagnosis and Treatment
11.38
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