Cardiovascular health, genetic predisposition, and dementia risk among atherosclerotic cardiovascular disease patients
Higher CVH levels were associated with a lower risk of VaD, not AD, with a stronger association in individuals with low GRS. Improvements in specific LE8 components, particularly sleep health and blood glucose management, were associated with reduced VaD risk across various genetic risk strata.
Authors
- Qingmei Cui
- Lingyan Dai
- Yuhu Zhang (ORCID: https://orcid.org/0000-0003-3492-4669)
- Chunxiang Jiang (ORCID: https://orcid.org/0000-0001-6960-4433)
- Li Huang
- Jie Li (ORCID: https://orcid.org/0000-0003-3902-642X)
- Siqi Chen (ORCID: https://orcid.org/0000-0002-9498-3823)
- Yidan Zhang (ORCID: https://orcid.org/0000-0001-6691-5244)
- Piao Zhang (ORCID: https://orcid.org/0000-0002-8941-7042)
- Xiaoyi Luo
Institutions
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- The Journal of Prevention of Alzheimer s Disease
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.tjpad.2024.100020
- Citations
- 3
- Primary Topic
- Cardiovascular Health and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 4.16
Funders
- National Natural Science Foundation of China
- Guangxi Key Research and Development Program