Efficacy of caerulomycin A in modulating macrophage polarization and cytokine response in a murine model of lipopolysaccharide-induced sepsis

CaeA effectively modulates macrophage polarization and attenuates the inflammatory response in septic mice, possibly by affecting the JAK-STAT signaling pathway. These findings support further exploration of the potential of caeA as a therapeutic agent for sepsis.

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Publication Details

Journal
European journal of medical research
Published
2025-01-10
DOI
https://doi.org/10.1186/s40001-024-02265-w
Citations
1
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
0.80
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article

Efficacy of caerulomycin A in modulating macrophage polarization and cytokine response in a murine model of lipopolysaccharide-induced sepsis

Shiyue Tang, Jun Zhang
1 citations
European journal of medical research
Immune cells in cancer
0.80
article

Efficacy of caerulomycin A in modulating macrophage polarization and cytokine response in a murine model of lipopolysaccharide-induced sepsis

Shiyue Tang, Jun Zhang
article en
1 citations

Abstract

CaeA effectively modulates macrophage polarization and attenuates the inflammatory response in septic mice, possibly by affecting the JAK-STAT signaling pathway. These findings support further exploration of the potential of caeA as a therapeutic agent for sepsis.

European journal of medical researchVol. 30(1)
Jinhua Central Hospital (CN)
Zero hunger
Openalex Percentile: Top 32%
Immune cells in cancer
0.80
DOIOpen Access PDFOpenAlex
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Efficacy of caerulomycin A in modulating macrophage polarization and cytokine response in a murine model of lipopolysaccharide-induced sepsis — Shiyue Tang, Jun Zhang · European journal of medical research (2025) | TGRS Research Map | TGRS