Individual patient and donor seroprofiles in convalescent plasma treatment of COVID-19 in REMAP-CAP clinical trial
Based on our data, increased S-antibody levels linked to transfused CP were only observed in pre-seroconversion or immunodeficient patients lacking their own SARS-CoV-2 antibodies, representing the groups where CP treatment has previously shown most benefit.
Authors
- Abigail Lamikanra (ORCID: https://orcid.org/0000-0002-9287-2177)
- Gestur Vidarsson (ORCID: https://orcid.org/0000-0001-5621-003X)
- Klaus Hedman (ORCID: https://orcid.org/0000-0003-1779-7960)
- Richard Mayne (ORCID: https://orcid.org/0000-0003-1915-4993)
- Manu Shankar‐Hari (ORCID: https://orcid.org/0000-0002-5338-2538)
- Lise J Estcourt (ORCID: https://orcid.org/0000-0003-4309-9162)
- Tonći Šuštić (ORCID: https://orcid.org/0000-0003-0559-6803)
- C. Ellen van der Schoot (ORCID: https://orcid.org/0000-0002-8065-3540)
- Hoi Pat Tsang
- Hannia Liliana Almonacid-Mendoza
- Visa Nurmi (ORCID: https://orcid.org/0000-0001-8052-5592)
- Heli Harvala (ORCID: https://orcid.org/0000-0001-9154-4190)
- David Krishna Menon (ORCID: https://orcid.org/0000-0002-3228-9692)
- Chanice Knight
- Jussi Hepojoki (ORCID: https://orcid.org/0000-0001-5699-214X)
- Shannah Secret
- David Roberts (ORCID: https://orcid.org/0000-0001-5955-0574)
- Peter Simmonds (ORCID: https://orcid.org/0000-0002-7964-4700)
Institutions
- NHS Blood and Transplant (GB)
- University of Helsinki (FI)
- Utrecht University (NL)
- University of Zurich (CH)
- University of Cambridge (GB)
- Helsinki University Hospital (FI)
- Sanquin (NL)
- University of Oxford (GB)
- Medawar Building for Pathogen Research (GB)
- Centre for Inflammation Research (GB)
- University of Edinburgh (GB)
Publication Details
- Journal
- Journal of Infection
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1016/j.jinf.2025.106412
- Citations
- 4
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 5.58
Funders
- NHS Blood and Transplant
- Magnus Ehrnroothin Säätiö
- Sigrid Juséliuksen Säätiö