Palladium-catalyzed allylic C–H alkylation of terminal olefins with 3-carboxamide oxindoles
A novel palladium-catalyzed allylic C-H alkylation of terminal olefins with 3-carboxamide oxindoles is described. A variety of new 3-carboxamide-3-allylation oxindoles with an all-carbon quaternary center were obtained in moderate to good yields (up to 99%). In addition, the asymmetric version of this reaction was also explored, providing moderate enantioselectivity.
Authors
- Dong Zhang (ORCID: https://orcid.org/0000-0002-3020-3218)
- Guansai Liu (ORCID: https://orcid.org/0000-0001-8925-6093)
- Guojuan Liang
- Hui Zhou (ORCID: https://orcid.org/0000-0001-7018-3277)
- Pengfei Zhou (ORCID: https://orcid.org/0000-0003-0077-8739)
- Jing Zhou (ORCID: https://orcid.org/0000-0003-3780-6107)
- Ning Zhang (ORCID: https://orcid.org/0000-0003-3516-1907)
- Xing Liu (ORCID: https://orcid.org/0000-0002-8448-9696)
- Dexin Zhang (ORCID: https://orcid.org/0009-0005-3235-7148)
Institutions
- Chongqing Medical and Pharmaceutical College (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d4ob01991a
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Chongqing
- Chongqing Municipal Education Commission